John Stamos shuts down rumors about leaving his wife for ex Full House co-star Lori Loughlin, revealing the truth about their long friendship and any past romantic sparks.
John Stamos is putting to rest any lingering rumors about his relationship with his former Full House co-star Lori Loughlin. The 62-year-old actor recently spoke candidly about his friendship with Loughlin on the Good Guys podcast, addressing years of speculation about whether their on-screen chemistry ever translated into real life.
A Close Friendship, But No Romance

Stamos and Loughlin, who portrayed Uncle Jesse and Aunt Becky on the iconic sitcom Full House (1987–1995) and later reprised their roles in Netflix’s Fuller House (2016–2020), have shared a deep bond for decades. Fans have long speculated whether their off-screen friendship ever turned into something more, especially given the undeniable chemistry between the two characters. However, Stamos set the record straight during his podcast interview, saying there was never any romantic involvement between them.
“We never had a romantic spark, but we might have kissed once,” Stamos revealed. He went on to explain that he once referred to Loughlin as “the one that got away” in a past interview, but it was never meant to suggest anything serious. “There was a very small window where we were both single at the same time,” Stamos explained, referencing his memoir, If You Would Have Told Me, published in 2023.
Describing His Type

Stamos compared Loughlin’s sweetness to Sandy from Grease—“before the leather”—and joked that his ex-wife Rebecca Romijn was more like Sandy after the leather. However, he made it clear that rebellious women were more his type. “Lori was so sweet, and I loved working with her, but she was too nice for me,” he admitted.
When pressed by podcast hosts Ben Soffer and Josh Peck on whether he would ever consider leaving his wife, Caitlin McHugh, for Loughlin, Stamos had a sharp response: “No f***ing way! I’m not Mormon. Do you do that with your wife? Are you a swinger?”
A Steamy Memory (Maybe)
While the friendship between Stamos and Loughlin was always platonic, Stamos shared an amusing anecdote about a moment he believed they had shared. “I always thought that we made out on some ride at Disneyland,” he said. “I remembered, I think she said it didn’t happen. So, I don’t know if it was something I made up in my mind. You know, some kind of fantasy.”
Supporting Loughlin Through Tough Times

Recently, Loughlin has faced significant personal challenges, including a reported separation from her husband of nearly 28 years, fashion designer Mossimo Giannulli. Stamos shared that he and Caitlin have been there for Loughlin during this tough time. “She lives in my neighborhood, and so I was over there a lot. She came to our house a couple of times, and Caitlin’s been good about it,” Stamos said. “I’m just heartbroken for her right now. She’s devastated.”
Loughlin’s separation from Giannulli follows the couple’s involvement in the college admissions scandal, and though they haven’t filed for divorce, the news has rocked the former Full House star.
Conclusion
John Stamos’ candid comments about Lori Loughlin put any rumors of romance to rest while highlighting the deep, enduring friendship between them. As Loughlin navigates personal challenges, Stamos has been a supportive friend, with Caitlin McHugh also offering her support. Despite their closeness, Stamos made it clear that his heart belongs to his wife, and he has no intentions of leaving her.